Publications (Newest to Oldest)

27. Jarvis, K., M. A. Woodward, E. P. Debold and S. Walcott, Acidosis affects muscle contraction by slowing the rates myosin attaches to and detaches from actin. Journal of Muscle Research and Cell Motility, In Press. PDF

 

26. Copos, C. A., S. Walcott, J. C. del Alamo, E. Bastounis, A. Mogilner and R. D. Guy, Mechanosensitive adhesion explains stepping motility in amoeboid cells.  Biophysical Journal, 112(12): 2672-2682, 2017.  PDF

 

25. Lombardo, A.T., S. R. Nelson, M. Y. Ali, G. G. Kennedy, K. M. Trybus, S. Walcott, and D. M. Warshaw, Myosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro.  Nature Communications, 8: 15692, 2017. PDF

 

24. Longyear, T., S. Walcott*, and E. P. Debold*, The molecular basis of thin filament activation: from single molecule to muscle.   Scientific Reports, 7: 1822, 2017. PDF

(*EPD and SW contributed equally)

 

23. Walcott, S., Kad, N. M., Direct measurements of local coupling between myosin molecules are consistent with a model of muscle activation.  PLoS Computational Biology, 11(11): e1004599, 2015. PDF

 

22.  Walcott, S., Docken, S. and Harris, S. P., Effects of cardiac myosin binding protein-C on actin motility are explained with a drag-activation-competition model.  Biophysical Journal (Letter), 108(1): 10-13, 2015. PDF

 

21. Walcott, S., Muscle activation described with a differential equation model for large ensembles of locally coupled molecular motors.  Physical Review E, 90(4):042717, 2014.  PDF

 

20. Debold, E.P.*, Walcott, S.*, Woodward, M. and Turner, M. A., Direct observation of phosphate inhibiting the force generating capacity of a mini ensemble of myosin molecules. Biophysical Journal, Volume 105, pages 2374-2384. 2013.  PDF

(*EPD and SW contributed equally)

 

19. Walcott, S., A differential equation model for tropomyosin-induced myosin cooperativity describes myosin-myosin interactions at low calcium, Cellular and Molecular Bioengineering, 6(1):13-25, 2013. PDF

 

18. Walcott, S., Warshaw, D. M. and Debold, E. P., Mechanical coupling between myosin molecules causes differences between ensemble and single-molecule measurements, Biophysical Journal, 103(3):501-510, 2012. PDF

 

17. Kim, D-H., Katau, S. B., Feng. Y., Walcott, S., Sun, S. X., Longmore, G. D., Wirtz, D., Actin cap associated focal adhesions and their distinct role in cellular mechanosensing. Scientific Reports. 2:555. 2012. PDF

16. Walcott, S., Kim, D-H., Wirtz, D., Sun, S. X. Nucleation and decay initiation are the stiffness sensitive phases of focal adhesion maturation. Biophysical Journal 101(12):2919-2928, 2011. PDF

15. Debold, E.P., Turner, M., Stout, J.C. and Walcott, S. Phosphate enhances myosin-powered actin filament velocity under acidic conditions in a motility assay. American Journal of Physiology (Regul. Integr. & Comp.) 300:R1401-R1408, 2011. PDF

14. Harland, B, Walcott, S., Sun, S. X., Adhesion dynamics and durotaxis in migrating cells. Physical Biology, 8(1):015011, 2011. PDF

13. Walcott, S, Sun, S. X., Active force generation in cross-linked filament bundles without motor proteins. Physical Review E, 82(5):050901, 2010. PDF

12. Sun, S. X., Walcott, S., Repairing the sense of touch. Current Biology, 20(20):R895-896, 2010. PDF

11. Walcott, S, Warshaw, D. M., Modeling smooth muscle myosin's two heads: long-lived enzymatic roles and phosphorylation-dependent equilibria. Biophysical Journal, 99(4):1129-1138, 2010.
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10. Sun, S. X., Walcott, S., Wolgemuth, C. W., Cytoskeletal cross-linking and bundling in motor-independent contraction. Current Biology, 20(15):R649-654, 2010.
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9. Walcott, S., Sun, S. X., A mechanical model of stress fiber formation and substrate elasticity sensing in adherent cells. Proceedings of the National Academy of Sciences, 107(17):7757-7762, 2010.
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8. Srinivasan, M, Walcott, S., (equal author contribution), Binding site models of friction due to the formation and rupture of bonds. Physical Review E. 80(4):046124, 2009. PDF


7. Walcott, S, Fagnant, P. M, Trybus, K. M., Warshaw, D. M., Smooth muscle myosin phosphorylated on one of its two heads supports force and motion. Journal of Biological Chemistry, 284(27):18244-18251, 2009.
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6. Walcott, S., Sun, S. X., Hysteresis in cross-bridge models of muscle. Physical Chemistry Chemical Physics, 11(24):4871-4881, 2009.
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5. Walcott, S., Kad, N. M., Theoretical prediction of the run speed distribution for a molecular motor. ASME Conference Proceedings, 2008(2):437-446, 2008.
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4. Walcott, S., Herzog, W., Modeling residual force enhancement with generic cross-bridge models. Mathematical Biosciences, 216(2):172-186, 2008. PDF

3. Walcott, S., The load-dependence of rate constants. Journal of Chemical Physics 128(21):215101, 2008. PDF

2. Walcott, S., Lehman, S. L., Enzyme kinetics of muscle glycogen phosphorylase b. Biochemistry, 46(42):11957-11968, 2007.

1. Walcott S., Storing kinetic energy: another explanation for countermovement in throwing. Engineering of Sport, 5(1): 209–215, 2004.