Mathematics Colloquia and Seminars

In order to study movements of actin-propelled beads, we use stochastic simulations of "in silico" actin network, in which microscopic individual actin filaments undergoing nucleation, elongation, attachment, detachment and capping are embedded in nodes-and-springs viscoelastic network representing macroscopic actin gel. Our study shows that the combined effects of macroscopic elastic deformation and microscopic ratchet are crucial for explanation of the observed force-velocity relations and orientations of the actin-propelled ellipsoidal beads.