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Phylogenomics: Inverting Random Trees

Probability

Speaker: Sebastian Roch, University of Wisconsin
Location: zoom
Start time: Wed, Apr 7 2021, 4:10PM

Phylogenomic analysis, in particular the estimation of species phylogenies from genome-scale data, is a common step in modern evolutionary studies. This estimation is complicated by the fact that genes evolve under biological processes that produce discordant trees. Such processes include horizontal gene transfer (HGT), incomplete lineage sorting (ILS), and gene duplication and loss (GDL), all of which can been modeled using specialized random tree distributions. I will survey some recent results regarding the analysis of these probabilistic models. Specifically their identifiability, or "invertibility", will be discussed as well as the asymptotic properties of species tree estimation methods (time permitting). Based on joint works with Max Bacharach, Brandon Legried, Erin Molloy, Elchanan Mossel, Allan Sly, Tandy Warnow, Shuqi Yu.