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Extending Boundary Integral Methods to Biofilm Dynamics
Mathematical Biology| Speaker: | Nick Cogan, Florida State University |
| Location: | 2112 MSB |
| Start time: | Mon, Jan 28 2008, 2:10PM |
Description
Current research has determined that that the majority of
bacteria in nature exist in structured communities termed biofilms rather
than free swimming planktonic bacteria. Moreover, bacteria within
biofilms are highly tolerant to typical antimicrobial and antibiotic
treatments. These observations, coupled with the negative impacts of the
presence of biofilms in medical, industrial and natural settings, have
driven research into the processes that govern the formation, growth and
development of biofilms.
Because biofilms typically form in the presence of an externally driven
fluid, the dynamics of the viscoelastic biofilm is inherently a fluid
dynamics problem. Biofilms are physically and biologically
heterogeneous with a range material properties, making any mathematical
treatment both challenging and engaging. This talk will describe the
incremental process of extending a classical technique used to
solve coupled flow problems (BIM) to incorporate the growth and material
properties of the biofilm. The goal of the research is to provide insight
into the mechanisms of bacterial tolerance and the development of more
effective removal of the bacteria.
