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GGAM PhD Exit Seminar: David Haley

Special Events

Speaker: David Haley
Location: ZOOM
Start time: Mon, Jun 7 2021, 4:10PM


Designing engineered molecular systems typically requires specialized knowledge of the particular substrate; however, one can also reason about such systems in a substrate-independent fashion, by examining the underlying energetics that govern any chemical substrate: the formation of molecular bonds and the number of complexes formed. The thermodynamic binding networks (TBN) model was developed to study such systems, and in particular, to determine fault-tolerance in molecular systems such as DNA strand displacement cascades. This general-audience talk will give an overview of the model and present some modular constructions exhibiting catalytic and autocatalytic behavior. Connections between facets of the model to Hilbert bases and to the social golfers problem will be demonstrated.